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The BIOFIRE System and Your Immune System The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare providers to choose the appropriate test first time. Patients benefit from quicker diagnosis and more specific treatment. Clinicians benefit from improved stewardship of antibiotics. Labs save money and gain efficiency. The BioFire FilmArray Pneumonia plus panel (PN panel) examines native sputum, endotracheal aspirate, and bronchoalveolar specimens (including mini-BAL) for 33 pathogens with clinical relevance and antimicrobial resistance genes. The panel provides semiquantitative results that take less than an hour. Respiratory The burning of biomass (wood, plants and other organic materials) produces gaseous pollutants as well as fine particles of matter that adversely affect the respiratory system. Furthermore, the environmental issues caused by forest fires, like droughts, could be potentiated by climate change, thereby increasing the negative effects on the health of humans. In the United States, wildfire smoke has been linked to respiratory diseases like asthma, COPD and lung cancer. This type of pollution to the air also increases the risk of developing cardiovascular diseases, and is a major contributor to the burden of disease among the most vulnerable populations. The wildfires have caused unhealthy levels of air pollution in many communities during the COVID-19 epidemic. The response to public health has been limited to a communication campaign on the management of symptoms. This gap in knowledge is concerning given the evidence of potential health risks resulting from the continual exposure to smoke and other sources of poor air quality. Researchers are now looking at the best ways to protect public health in future events of this kind. NIH invests in research on this critical public health issue through the BLUE CORAL and FIRE CORAL studies. For the first time, a prospective cohort study will assess long-term outcomes from exposure to smoke from wildfires as well as other sources. FIRE CORAL recruits adult participants who are hospitalized for COVID-19 index episodes and speak English or Spanish, but are not pregnant. The protocol for Fire Coral includes a series of in-person assessments that objectively measure the pulmonary function testing and lung imaging, as well as functional assessment. Smoke and other particles can trigger or worsen respiratory problems such as emphysema, COPD and pneumonia. Smoke exposure can have adverse effects on health. To reduce or prevent these effects, avoid outdoor activities and wear the EPA “N95” mask. The mask is designed to capture small particles. Smoking cigarettes can cause irritation to the eyes and throat, and cause the nose to run. To minimize Fireplaces And Stove need to be flushed by drinking plenty of fluids and taking medications that reduce inflammation, such as corticosteroids. Bloodstream The bloodstream is the first line of defense against germs that enter your system. Dendritic cells, which are special cells, act as a call center for your fire department. They are able to collect antigens from germs and release proteins that signal other white cells to fight. The total number of white blood cells, differentials, and band cells increased following firefighters' firefighting activities as compared to levels following intense exercise without firefighting. Skin Dermatologists were concerned that smoke and ash of the California wildfires could have negative effects on the skin of those exposed to them. Maria Wei, a graduate student at the University of California, Irvine is studying how severe wildfire pollution affects the skin. Her research was published on April 22 2012 in Scientific Reports. The study by Wei shows that temperature changes of the skin according to the length of time the body has been exposed. It could take up to two hours for the skin of a person to reach its “flash point”—the point where it begins to burn and turn ashy. It is important to avoid staying near a campfire or fire and wear protective clothing if going outside on a hot or humid day. Forest fires will continue happen, despite the precautions taken to prevent wildfire pollution. Wei predicts that as climate change causes forests to burn more quickly, the number of people who suffer from wildfires will rise. That means more people will need to wear long sleeves, hats and thick moisturizers. Wildfire air pollution can also exacerbate atopic skin dermatitis, which is a condition that causes itchy skin in many people. The reason for this is due to the particles in smoke can block pores, which makes atopic dermatitis worse. Atopic dermatitis can make people more sensitive towards UV light. This is often exacerbated by smoke from wildfires. This can lead to people seeking out tanning salons to get tanned with less protection. A treatment with ice and fire can help reduce atopic skin dermatitis symptoms however, it isn't recommended for anyone with an open wound or rash. Patients with active acne should be cautious, and if you're nursing or pregnant, it is recommended to stay clear of this treatment completely. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' most prestigious membership MedSpa It's a highly effective, results-driven facial that bridges the gap between a gentle facial and a peel without requiring any downtime. It's designed to rejuvenate skin, improve rosacea and reduce the appearance of acne scars and fine lines and stimulate cellular renewal. It's an incredible treatment to give yourself radiant skin. Infections The human body is a complex system of organs and tissues that work to protect us from infections. Infections are caused by microscopic microorganisms like bacteria, viruses, parasites and fungus that invade healthy cells and cause them to reproduce out of control. If this occurs your immune system could react with symptoms of illness. The symptoms could range from a runny nose to a stomach that is upset, but can also include a fever, swollen lymph glands or an scratch. The type of infection and its location can impact the symptoms. Infections can be spread through a variety of methods but the most prevalent are transmitted from person to person through droplets that linger in the air after sneezing or coughing. Bacterial infections like strep throat, tuberculosis, meningococcal diseases and Legionnaires' disease are spread through this method, along with certain viral infections such as the common cold and influenza. Certain bacterial infections like skin infections or sexually transmitted diseases (STIs) such as Chlamydia and gonorrhea can be transmitted by direct contact with infected mucous surfaces or tissues, or indirectly through surfaces that are contaminated. Some bacterial diseases are transmitted by insects like mosquitoes, ticks or fleas. They can be spread when these bugs bite you. Some parasites and viruses are small enough to penetrate your bloodstream and infect your cells, which leads to serious illnesses like the common cold or AIDS. Fungi can cause skin conditions like ringworm and athlete's feet and others can infect the lungs and nervous system. The BioFire Panel uses our innovative FilmArray technology to analyze sputum and bronchoalveolar fluid samples to provide a complete list of pathogens that are involved in upper respiratory infections. The kit comes with an reagent pouch that houses all the necessary chemicals to perform reverse transcription PCR, nested testing and detection with a single device. It's a simple-to-use tool to aid clinicians in identifying and treat patients with a variety of respiratory symptoms. This test has been given an Emergency Use Authorization. It's available in bioMerieux CLIA medium and high-complex laboratories.